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SMCR7L polyclonal antibody

货号: BS31262

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

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No. :BS31262

Product Name :SMCR7L polyclonal antibody

Swiss-Prot :Q9NQG6

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/2000)

Background :Mitochondrial dynamics protein MIEF1: Mitochondrial outer membrane protein which regulates mitochondrial fission/fusion dynamics . Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of SMCR7L protein

BiowMW :~51.3 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MID51; SMCR7L; Mitochondrial dynamics protein MID51; Mitochondrial dynamics protein of 51 kDa; Mitochondrial elongation factor 1; Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like; SMCR7-like protein

Immunogen :Recombinant fusion protein of human SMCR7L.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of SRF (Phospho-S103) expression in HeLa (A), Jurkat (B) whole cell lysates.