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HVCN1 polyclonal antibody

货号: BS31232

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31232

Product Name :HVCN1 polyclonal antibody

Swiss-Prot :Q96D96

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/2000)

Background :Voltage-gated hydrogen channel 1: Voltage-gated proton-selective channel that conducts outward proton currents in response to intracellular acidification. Lacks a canonical ion-channel pore domain and mediates proton permeability via its voltage sensor domain . Appears to play a dominant role in regulation of CO2/HCO3(-)/H(+) equilibrium in sperm flagellum. Prevents the acidification resulting from HCO3(-) synthesis and thus sustains high HCO3(-) levels inside sperm for capacitation . Provides for proton efflux that compensates for electron charge generated by NADPH oxidase activity either in the extracellular or phagosomal compartments, thus enabling the production of high levels of bactericidal reactive oxygen species during the respiratory burst . Opens when the pH of airway surface liquid exceeds 7 and contributes to respiratory epithelial acid secretion to maintain pH in the mucosa

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of HVCN1 protein

BiowMW :~31.7 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :VSOP; Voltage-gated hydrogen channel 1; Hydrogen voltage-gated channel 1; HV1; Voltage sensor domain-only protein

Immunogen :Recombinant fusion protein of human HVCN1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Calpain 1 expression in A431 (A), A549 (B), MCF7 (C), U251 MG (D) whole cell lysates.

免疫沉淀（IP）