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NRF2 polyclonal antibody

货号: BS6286

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS6286

Product Name :NRF2 polyclonal antibody

Swiss-Prot :Q16236

Host :Rabbit

Reactivity :Human, Mouse, Rat, Pig

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF/ICC,1:100 - 1:500

Background :This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :NRF2 polyclonal antibody detects endogenous levels of NRF2 protein.

BiowMW :110KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NFE2L2;HEBP1;NRF2

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human NRF2.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of NRF2 expression in HEK293T (A), A549 (B) whole cell lysates.

Immunohistochemical analysis of NRF2 staining in human lung cancer formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of NRF2 staining in HL60 cells.

PGD2 and PGE2 regulate gene expression of Prx 6 in primary macrophages via Nrf2

JournalFree Radical Biology And Medicine

ApplicationWB

IF7.376

SpeciesMouse

PMID
Oxymatrine prevents hypoxia- and monocrotaline-induced pulmonary hypertension in rats

JournalFree Radical Biology And Medicine

ApplicationWB

IF7.376

SpeciesRat

PMID24440469
Sodium hydrosulfide alleviates lung inflammation and cell apoptosis following resuscitated hemorrhagic shock in rats

JournalActa Pharmacologica Sinica

ApplicationWB

IF6.15

SpeciesRat

PMID
Drug resistance associates with activation of Nrf2 in MCF-7/DOX cells, and wogonin reverses it by down-regulating Nrf2-mediated cellular defense response

JournalMolecular Carcinogenesis

ApplicationWB

IF4.784

SpeciesHuman

PMID
Attenuation of Cigarette Smoke-Induced Airway Mucus Production by Hydrogen-Rich Saline in Rats

JournalPLoS One

ApplicationWB

IF2.776

SpeciesRat

PMID24376700