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NRF2 polyclonal antibody

货号: BS6286

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6286

Product Name :NRF2 polyclonal antibody

Swiss-Prot :Q16236

Host :Rabbit

Reactivity :Human, Mouse, Rat, Pig

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF/ICC,1:100 - 1:500

Background :This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :NRF2 polyclonal antibody detects endogenous levels of NRF2 protein.

BiowMW :110KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NFE2L2;HEBP1;NRF2

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human NRF2.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of NRF2 expression in HEK293T (A), A549 (B) whole cell lysates.

Immunohistochemical analysis of NRF2 staining in human lung cancer formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of NRF2 staining in HL60 cells.

Therapeutic Potential of Perillaldehyde in Ameliorating Vulvovaginal Candidiasis by Reducing Vaginal Oxidative Stress and Apoptosis

JournalAntioxidants

ApplicationWB

IF6.312

SpeciesMouse

PMID
Moringa oleifera mitigates ethanol-induced oxidative stress, fatty degeneration and hepatic steatosis by promoting Nrf2 in mice

JournalPhytomedicine

ApplicationIHC,WB

IF5.34

SpeciesMouse

PMID35358929
Dimethyl Bisphenolate Ameliorates Carbon Tetrachloride-Induced Liver Injury by Regulating Oxidative Stress-Related Genes

JournalMOLECULES

ApplicationWB,IF

IF4.6

SpeciesRat,Human

PMID38138479
Activation of the AMPK/Nrf2 pathway ameliorates LPS-induced acute lung injury by inhibiting oxidative stress and reducing inflammation

Journal10.1186/s13019-024-03020-2

ApplicationWB

IF1.5

SpeciesMouse

PMID39354500
SMND-309 activates Nrf2 signaling to alleviate acetaminophen-induced hepatotoxicity and oxidative stress

JournalPLoS One

ApplicationIF,WB

IF2.9

SpeciesMouse,Human

PMID40163430