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NRF2 polyclonal antibody

货号: BS6286

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS6286

Product Name :NRF2 polyclonal antibody

Swiss-Prot :Q16236

Host :Rabbit

Reactivity :Human, Mouse, Rat, Pig

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:1000|IHC,1:50 - 1:200|IF/ICC,1:100 - 1:500

Background :This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :NRF2 polyclonal antibody detects endogenous levels of NRF2 protein.

BiowMW :110KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NFE2L2;HEBP1;NRF2

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human NRF2.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of NRF2 expression in HEK293T (A), A549 (B) whole cell lysates.

Immunohistochemical analysis of NRF2 staining in human lung cancer formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of NRF2 staining in HL60 cells.

Apigenin, a modulator of PPARγ, attenuates HFD-induced NAFLD by regulating hepatocyte lipid metabolism and oxidative stress via Nrf2 activation

JournalBiochemical Pharmacology

ApplicationWB

IF4.825

SpeciesMouse

PMID28414138
Curcumin upregulates Nrf2 nuclear translocation and protects rat hepatic stellate cells against oxidative stress

JournalMolecular Medicine Reports

ApplicationWB,IHC

IF1.851

SpeciesRat

PMID26676408
Knockdown of a novel lincRNA AATBC suppresses proliferation and induces apoptosis in bladder cancer

JournalOncotarget

ApplicationWB

IF0

SpeciesHuman

PMID25473900
Comparison of protective effect of ordinary Cordyceps militaris and selenium-enriched Cordyceps militaris on triptolide-induced acute hepatotoxicity and the potential mechanisms

JournalJournal of Functional Foods

ApplicationWB

IF3.701

SpeciesRat

PMID
Administration of Donor-Derived Nonexpanded Adipose Stromal Vascular Fraction Attenuates Ischemia-Reperfusion Injury in Donation After Cardiac Death Rat Renal Transplantation

JournalTransplantation Proceedings

ApplicationWB

IF1.066

SpeciesRat

PMID34266654