Product Name :CD178 monoclonal antibody
Background :Tumor necrosis factor ligand superfamily member 6: Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells . Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development . Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses . TNFRSF6/FAS-mediated apoptosis also has a role in the induction of peripheral tolerance . Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis (By similarity)
Product :Armenian Hamster IgG. 1mg/ml in PBS, pH 7.3, and 0.02% sodium azide.
Purification&Purity :The antibody was purified by affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes mouse CD178
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :APT1LG1; CD95L; FASL; TNFSF6; Tumor necrosis factor ligand superfamily member 6; Apoptosis antigen ligand; APTL; CD95 ligand; CD95-L; Fas antigen ligand; Fas ligand; FasL; CD178
Immunogen :Native purified mouse CD178
Modification :Unmodification
