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CD33 monoclonal antibody

货号: MB23520

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB23520

Product Name :CD33 monoclonal antibody

Swiss-Prot :P20138

Host :Mouse

Reactivity :Human

Applications :WB,IHC,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 FC:1/200 - 1/400

Background :The protein encoded by this gene belongs to putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro) and CD33 plays potential key roles in the pathogenesis of Alzheimer's disease (AD)

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :39.8kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :p67; SIGLEC3; SIGLEC-3

Immunogen :Purified recombinant fragment of human CD33 (AA: 15-237) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Westemn blot analysis usingCDs3 mouse mAb against THP-1 (1call lysate.

Immunohistochemical analysis of parafin-embedded esophagea cancer tssues using CD33 mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）