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TDP43 monoclonal antibody

货号: MB23487

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB23487

Product Name :TDP43 monoclonal antibody

Swiss-Prot :Q13148

Host :Mouse

Reactivity :Human

Applications :WB,IHC,IF,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]</p>

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :44.7kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ALS10; TDP-43

Immunogen :Purified recombinant fragment of human TDP43 (AA: free peptide) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using TDP43 mouse mAb against Hela (1), HEK293 (2), MCF-7 (3), and A549 (4) cell lysate.

Immunohistochemical analysis of paraffin-embedded human baldder cancer tissues using TDP43 mouse mAb with DAB staining.

Immunofluorescence analysis of Hela cells using TDP43 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of A431 cells using TDP43 mouse mAb (green) and negative control (red).