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JAM3 monoclonal antibody

货号: MB23423

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB23423

Product Name :JAM3 monoclonal antibody

Swiss-Prot :Q9BX67

Host :Mouse

Reactivity :Human

Applications :WB,FCM

Application_all :WB:1/500 - 1/2000 FC:1/200 - 1/400

Background :Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :35kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :JAMC; JAM-2; JAM-3; JAM-C

Immunogen :Purified recombinant fragment of human JAM3 (AA: extra 32-241) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using JAM3 mouse mAb against SH-SY5Y (1) cell lysate.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）