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HNF1B monoclonal antibody

货号: MB23420

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB23420

Product Name :HNF1B monoclonal antibody

Swiss-Prot :P35680

Host :Mouse

Reactivity :Human, Mouse, Rat

Applications :WB,IHC,IF,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 IF:1/50 - 1/200 FC:1/200 - 1/400

Background :This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2a

BiowMW :61.3kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :T2D; FJHN; HNF2; LFB3; RCAD; TCF2; HPC11; LF-B3; MODY5; TCF-2; VHNF1; ADTKD3; HNF-1B; HNF1beta; HNF-1-beta

Immunogen :Purified recombinant fragment of human HNF1B (AA: 23-132) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using HNF1B mouse mAb against Hela (1) cell lysate.

Immunohistochemical analysis of paraffin-embedded rat kidney tissues using HNF1B mouse mAb with DAB staining.

Immunofluorescence analysis of Hela cells using HNF1B mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of PC-3 cells using HNF1B mouse mAb (green) and negative control (red).