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COL2A1 monoclonal antibody

货号: MB23403

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB23403

Product Name :COL2A1 monoclonal antibody

Swiss-Prot :P02458

Host :Mouse

Reactivity :Human

Applications :WB,IF,FCM

Application_all :WB:1/500 - 1/2000 IF:1/50 - 1/200 FC:1/200 - 1/400

Background :This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :141.8kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :AOM; ANFH; SEDC; STL1; COL11A3

Immunogen :Purified recombinant fragment of human COL2A1 (AA: 1222-1487) expressed in HEK293-6e cells supernatant.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using COL2A1 mouse mAb against Hela (1), MCF-7 (2),A549 (3),Jurkat (4), and K562 (5) cell lysate.

Immunofluorescence analysis of Hela cells using COL2A1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)