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CEACAM6 monoclonal antibody

货号: MB23162

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB23162

Product Name :CEACAM6 monoclonal antibody

Swiss-Prot :P40199

Host :Mouse

Reactivity :Human, Mouse, Rat

Applications :WB,IHC,IF,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 IF:1/25 - 1/100 FC:1/200 - 1/400

Background :This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19.</p>

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :37.2kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NCA; CEAL; CD66c

Immunogen :Purified recombinant fragment of human CEACAM6 (AA: 35-256) expressed in HEK293-6e cells supernatant.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using CEACAM6 mouse mAb against Jurkat (1), PC-12 (2), HEK293 (3), MG63 (4), and C2C12 (5) cell lysate.

Immunohistochemical analysis of paraffin-embedded human colon tissues using CEACAM6 mouse mAb with DAB staining.

Immunofluorescence analysis of Hela cells using CEACAM6 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of Jurkat cells using CEACAM6 mouse mAb (green) and negative control (red).