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CD105 monoclonal antibody

货号: MB23140

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB23140

Product Name :CD105 monoclonal antibody

Swiss-Prot :P17813

Host :Mouse

Reactivity :Human

Applications :WB,IHC,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 FC:1/200 - 1/400

Background :This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.</p>

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :70.6kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ENG; END; HHT1; ORW1

Immunogen :Purified recombinant fragment of human CD105 (AA: extra 342-586) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using CD105 mouse mAb against HUVEC (1), HUVE-12 (2), SH-SY5Y (3), and HEK293 (4) cell lysate.

Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using CD105 mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）