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ABCA1 monoclonal antibody

货号: MB23105

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB23105

Product Name :ABCA1 monoclonal antibody

Swiss-Prot :O95477

Host :Mouse

Reactivity :Human,Mouse,Rat,Rabbit,Monkey

Applications :IHC,IF,FCM

Application_all :IHC:1/100 - 1/500 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency.</p>

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2a

BiowMW :254 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TGD; ABC1; CERP; ABC-1; HDLDT1; HPALP1; HDLCQTL13

Immunogen :Purified recombinant fragment of human ABCA1 (AA: 2081-2261) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemical analysis of paraffin-embedded Mouse spleen using ABCA1 mouse mAb with DAB staining.

Immunofluorescence analysis of Hela cells using ABCA1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)