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CD43 monoclonal antibody

货号: MB22978

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB22978

Product Name :CD43 monoclonal antibody

Swiss-Prot :P16150

Host :Mouse

Reactivity :Human

Applications :WB,IHC,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200-1/1000 FC:1/200-1/400

Background :This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome.</p>

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :40.3kda

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :LSN; SPN; GALGP; GPL115

Immunogen :Purified recombinant fragment of human CD43(AA: extra(20-169)) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using CD43 mouse mAb against HEK293-6E (1), HEK293 (2),K562 (3), MOLT4 (4), Jurkat (5),and PANC-1 (6) cell lysate.

Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using CD43 mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）