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MAPK9 monoclonal antibody

货号: MB22797

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB22797

Product Name :MAPK9 monoclonal antibody

Swiss-Prot :P45984

Host :Mouse

Reactivity :Human

Applications :WB,FCM

Application_all :WB:1/500 - 1/2000 FC:1/200 - 1/400

Background :The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. </p>

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :48.1kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :JNK2; SAPK; p54a; JNK2A; JNK2B; PRKM9; JNK-55; SAPK1a; JNK2BETA; p54aSAPK; JNK2ALPHA

Immunogen :Purified recombinant fragment of human MAPK9 (AA: 227-382) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using MAPK9 mouse mAb against HEK293 (1) and U251 (2) cell lysate.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）