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KAT2B monoclonal antibody

货号: MB22710

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB22710

Product Name :KAT2B monoclonal antibody

Swiss-Prot :Q92831

Host :Mouse

Reactivity :Human,Mouse,Rat,Monkey

Applications :WB,IHC,IF,FCM

Application_all :IHC:1/200 - 1/1000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.</p>

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :93kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CAF; PCAF; P/CAF

Immunogen :Purified recombinant fragment of human KAT2B (AA: 1-142) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using KAT2B mouse mAb against C2C12 (1), COS7 (2), HepG2 (3), HCT116 (4), A431 (5), LNCAP (6), NIH/3T3 (7), and F9 (8) cell lysate.

Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using KAT2B mouse mAb with DAB staining.

Immunofluorescence analysis of Hela cells using KAT2B mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of MOLT4 cells using KAT2B mouse mAb (green) and negative control (red).