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PSMA monoclonal antibody

货号: MB22505

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB22505

Product Name :PSMA monoclonal antibody

Swiss-Prot :Q04609

Host :Mouse

Reactivity :Human

Applications :WB,FCM

Application_all :WB:1/500 - 1/2000 FC:1/200 - 1/400

Background :This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.<br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :84.3kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :FOLH1; PSM; FGCP; FOLH; GCP2; mGCP; GCPII; NAALAD1; NAALAdase

Immunogen :Purified recombinant fragment of human PSMA (AA: extra 44-177) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using PSMA mouse mAb against Hela (1), MCF-7 (2), HCT116 (3), and GC-7901 (4) cell lysate.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）