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CD183 monoclonal antibody

货号: MB22469

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB22469

Product Name :CD183 monoclonal antibody

Swiss-Prot :P49682

Host :Mouse

Reactivity :Human

Applications :WB,IHC,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 FC:1/200 - 1/400

Background :This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).<br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :40.7kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CXCR3; GPR9; MigR; CD182; Mig-R; CKR-L2; CMKAR3; IP10-R

Immunogen :Purified recombinant fragment of human CD183 (AA: extra mix) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using CD183 mouse mAb against Hela (1) and L-02 (2) cell lysate.

Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using CD183 mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）