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BCL2L2 monoclonal antibody

货号: MB22403

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB22403

Product Name :BCL2L2 monoclonal antibody

Swiss-Prot :Q92843

Host :Mouse

Reactivity :Human

Applications :WB,IHC,IF,FCM

Application_all :IHC:1/200 - 1/1000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. <br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2a

BiowMW :20.7kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :BCLW; BCL-W; PPP1R51; BCL2-L-2

Immunogen :Purified recombinant fragment of human BCL2L2 (AA: 6-118) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using BCL2L2 mouse mAb against HCT116 (1), LOVO (2), SW480 (3), and HL-60 (4) cell lysate.

Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using BCL2L2 mouse mAb with DAB staining.

Immunofluorescence analysis of Hela cells using BCL2L2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of Hela cells using BCL2L2 mouse mAb (green) and negative control (red).