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ATG5 monoclonal antibody

货号: MB22391

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB22391

Product Name :ATG5 monoclonal antibody

Swiss-Prot :Q9H1Y0

Host :Mouse

Reactivity :Human

Applications :WB,IF,FCM

Application_all :IF:1/100 - 1/500 FC:1/200 - 1/400

Background :The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.<br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2b

BiowMW :32.4kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ASP; APG5; APG5L; hAPG5; APG5-LIKE

Immunogen :Purified recombinant fragment of human ATG5 (AA: 144-275) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using ATG5 mouse mAb against K562 (1), SH-SY5Y (2), and HCT116 (3) cell lysate.

Immunofluorescence analysis of Hela cells using ATG5 mouse mAb. Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.