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CHRNA4 monoclonal antibody

货号: MB22378

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB22378

Product Name :CHRNA4 monoclonal antibody

Swiss-Prot :P43681

Host :Mouse

Reactivity :Human

Applications :FCM

Application_all :FC:1/200 - 1/400

Background :This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants.<br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :70kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :EBN; BFNC; EBN1; NACHR; NACRA4; NACHRA4

Immunogen :Purified recombinant fragment of human CHRNA4 (AA: extra 29-242) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using CHRNA4 mouse mAb against SH-SY5Y (1) cell lysate.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）