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CIRBP monoclonal antibody

货号: MB22285

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB22285

Product Name :CIRBP monoclonal antibody

Swiss-Prot :Q14011

Host :Mouse

Reactivity :Human

Applications :WB,IHC

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000

Background :Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3-untranslated regions (3-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.<br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :18.6kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CIRP

Immunogen :Purified recombinant fragment of human CIRBP (AA: 1-90) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using CIRBP mouse mAb against SW480 (1), PC-3 (2), A431 (3), and U251 (4) cell lysate.

Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using CIRBP mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）