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HLA-DRA monoclonal antibody

货号: MB22252

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB22252

Product Name :HLA-DRA monoclonal antibody

Swiss-Prot :P01903

Host :Mouse

Reactivity :Human

Applications :WB,IF,FCM

Application_all :WB:1/500 - 1/2000 IF:1/100 - 1/500 FC:1/200 - 1/400

Background :HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. <br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2b

BiowMW :28.6kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MLRW; HLA-DRA1

Immunogen :Purified recombinant fragment of human HLA-DRA (AA: 26-254) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using HLA-DRA mouse mAb against Ramos (1), and Raji (2) cell lysate.

Immunofluorescence analysis of Hela cells using HLA-DRA mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)