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BIN1 monoclonal antibody

货号: MB22189

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB22189

Product Name :BIN1 monoclonal antibody

Swiss-Prot :O00499

Host :Mouse

Reactivity :Human,Mouse

Applications :WB,FCM

Application_all :WB:1/500 - 1/2000 FC:1/200 - 1/400

Background :This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.<br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2b

BiowMW :64.7kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :AMPH2; AMPHL; SH3P9

Immunogen :Purified recombinant fragment of human BIN1 (AA: 189-398) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using BIN1 mouse mAb against Hela (1), C2C12 (2), A431 (3), and HEK293 (4) cell lysate.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）