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SK2 monoclonal antibody

货号: MB22042

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB22042

Product Name :SK2 monoclonal antibody

Swiss-Prot :Q9NRA0

Host :Mouse

Reactivity :Human

Applications :IHC,IF,FCM

Application_all :IHC:1/200 - 1/1000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.<br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :69.2kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SPHK2; SK-2; SPK 2; SPK-2

Immunogen :Synthesized peptide of human SK2 (AA: 36-52).

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissues using SK2 mouse mAb with DAB staining.

Immunofluorescence analysis of HeLa cells using SK2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)