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DDX39B monoclonal antibody

货号: MB22026

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB22026

Product Name :DDX39B monoclonal antibody

Swiss-Prot :Q13838

Host :Mouse

Reactivity :Human,Mouse

Applications :WB,IHC

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000

Background :This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and it also plays an important role in mRNA export from the nucleus to the cytoplasm. This gene belongs to a cluster of genes localized in the vicinity of the genes encoding tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on both chromosomes 6 and 11. Read-through transcription also occurs between this gene and the upstream ATP6V1G2 (ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2) gene.<br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :49kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :BAT1; UAP56; D6S81E

Immunogen :Purified recombinant fragment of human DDX39B (AA: 1-250) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using DDX39B mouse mAb against HEK293 (1), Jurkat (2), MCF-7 (3), A431 (4), NIH/3T3 (5), Jurkat (6), K562 (7), and HepG2 (8) cell lysate.

Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using DDX39B mouse mAb with DAB staining.