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HDAC2 monoclonal antibody

货号: MB21989

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21989

Product Name :HDAC2 monoclonal antibody

Swiss-Prot :Q92769

Host :Mouse

Reactivity :Human,Mouse,Monkey,Rat

Applications :WB,IHC,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 FC:1/200 - 1/400

Background :This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.<br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :55.4kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HD2; RPD3; YAF1

Immunogen :Purified recombinant fragment of human HDAC2 (AA: 217-327) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using HDAC2 mouse mAb against Hela (1), Jurat (2), HepG2 (3), Hek293 (4), K562 (5), MCF-7 (6), NIH3T3 (7), COS7 (8) and PC-12 (9) cell lysate.

Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using HDAC2 mouse mAb with DAB staining.