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ERBB4 monoclonal antibody

货号: MB21925

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21925

Product Name :ERBB4 monoclonal antibody

Swiss-Prot :Q15303

Host :Mouse

Reactivity :Human

Applications :IHC,FCM

Application_all :IHC:1/200 - 1/1000 FC:1/200 - 1/400

Background :This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.<br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :146.8kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HER4; ALS19; p180erbB4

Immunogen :Purified recombinant fragment of human ERBB4 (AA: 1159-1308) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using ERBB4 mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）