Product Name :PKD1 monoclonal antibody
Application_all :FC:1/200 - 1/400
Background :Involved in renal tubulogenesis. Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Acts as a regulator of cilium length, together with PKD2. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. May be an ion-channel regulator. Involved in adhesive protein-protein and protein-carbohydrate.<br />
Product :Purified antibody in PBS with 0.05% sodium azide
Purification&Purity :The antibody was affinity-purified from rat ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :PC1; Mflj00285
Immunogen :Purified recombinant fragment of mouse PKD1 (AA: 3682-3873) expressed in E. Coli.
Modification :Unmodification
