Product Name :PDGFRA monoclonal antibody
Reactivity :Human,Mouse,Monkey
Application_all :IF:1/50 - 1/500 FC:1/200 - 1/400
Background :This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
Product :Purified antibody in PBS with 0.05% sodium azide.
Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :CD140A; PDGFR2; PDGFR-2; RHEPDGFRA
Immunogen :Purified recombinant fragment of human PDGFRA (AA: 361-528) expressed in E. Coli.
Modification :Unmodification