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RB1 monoclonal antibody

货号: MB21780

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB21780

Product Name :RB1 monoclonal antibody

Swiss-Prot :P06400

Host :Mouse

Reactivity :Human

Applications :WB,FCM

Application_all :WB:1/500 - 1/2000 FC:1/200 - 1/400

Background :The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. <br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :106.2kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RB; pRb; OSRC; pp110; p105-Rb

Immunogen :Purified recombinant fragment of human RB1 (AA: 2106-2784) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using RB1 mouse mAb against Jurkat (1) and A431 (2) cell lysate.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）