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MCAM monoclonal antibody

货号: MB21707

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB21707

Product Name :MCAM monoclonal antibody

Swiss-Prot :P43121

Host :Mouse

Reactivity :Human

Applications :WB,IHC,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 FC:1/200 - 1/400

Background :The protein encoded by this gene plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. <br /><br />

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :71.6kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CD146; MUC18

Immunogen :Purified recombinant fragment of human MCAM (AA: 84-189) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using MCAM mouse mAb against HUVE-12 (1), EVC-304 (2), HELA (3) and MCF-7 (4) cell lysate.

Immunohistochemical analysis of paraffin-embedded human liver cancer tissues using MCAM mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）