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SQSTM1 monoclonal antibody

货号: MB21699

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21699

Product Name :SQSTM1 monoclonal antibody

Swiss-Prot :Q13501

Host :Mouse

Reactivity :Human,Mouse,Rat,Rabbit,Monkey

Applications :WB,IHC,IF,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 IF:1/100-1/200 FC:1/200 - 1/400

Background :This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :47.7kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :p60; p62; A170; OSIL; PDB3; ZIP3; p62B

Immunogen :Purified recombinant fragment of human SQSTM1 (AA: 232-356) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using SQSTM1 mouse mAb against Hela (1), Jurkat (2), THP-1 (3), HEK293 (4), A549 (5), MCF-7 (6), HepG2 (7), COS7 (8) and SK-BR-3 (9) cell lysate.

Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using SQSTM1 mouse mAb with DAB staining.

Immunofluorescence analysis of Rat cortical tissue using SQSTM1 mouse mAb (Red). Blue: DRAQ5 fluorescent DNA dye.