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KEAP1 monoclonal antibody

货号: MB21678

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21678

Product Name :KEAP1 monoclonal antibody

Swiss-Prot :Q14145

Host :Mouse

Reactivity :Human,Mouse

Applications :WB,IF,FCM

Application_all :IF:1/50 FC:1/200 - 1/400

Background :This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :69.7kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :INrf2; KLHL19

Immunogen :Purified recombinant fragment of human KEAP1 (AA: 380-624) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using KEAP1 mouse mAb against NIH3T3 (1), and A549 (2) cell lysate.

Immunofluorescence analysis of HeLa cells using KEAP1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.