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ILK monoclonal antibody

货号: MB21663

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21663

Product Name :ILK monoclonal antibody

Swiss-Prot :Q13418

Host :Mouse

Reactivity :Human,Mouse,Monkey

Applications :WB,IHC,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 FC:1/200 - 1/400

Background :Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Product :Ascitic fluid containing 0.03% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :51.4kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :P59; ILK-2

Immunogen :Purified recombinant fragment of human ILK (AA: 97-244) expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using ILK mouse mAb against Jurkat (1), NIH3T3 (2), HeLa (3), PC-12 (4), C6 (5), COS7 (6), Raji (7), K562 (8) and MCF-7 (9) cell lysate.

Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissues using ILK mouse mAb with DAB staining.