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NEFL monoclonal antibody

货号: MB21565

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21565

Product Name :NEFL monoclonal antibody

Swiss-Prot :P07196

Host :Mouse

Reactivity :Human

Applications :WB,IHC,IF,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

Product :Purified antibody in PBS with 0.05% sodium azide

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :62kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NFL; NF-L; NF68; CMT1F; CMT2E

Immunogen :Purified recombinant fragment of human NEFL expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using NEFL mouse mAb against Hela (1) and Jurkat (2) cell lysate.

Immunohistochemical analysis of paraffin-embedded human lung cancer tissues using NEFL mouse mAb with DAB staining.

Immunofluorescence analysis of Hela cells using NEFL mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Flow cytometric analysis of Jurkat cells using NEFL mouse mAb (green) and negative control (red).