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NQO1 monoclonal antibody

货号: MB21546

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21546

Product Name :NQO1 monoclonal antibody

Swiss-Prot :P15559

Host :Mouse

Reactivity :Human,Rat,Monkey

Applications :WB,IF,FCM

Application_all :WB:1/500 - 1/2000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Product :Ascitic fluid containing 0.03% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :31kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :DTD; QR1; DHQU; DIA4; NMOR1; NMORI

Immunogen :Purified recombinant fragment of human NQO1 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using NQO1 mouse mAb against A549 (1), Hela (2), MCF-7 (3) and HepG2 (4) cell lysate.

Immunofluorescence analysis of COS7 cells using NQO1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.