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KIT monoclonal antibody

货号: MB21516

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB21516

Product Name :KIT monoclonal antibody

Swiss-Prot :P10721

Host :Mouse

Reactivity :Human

Applications :WB,IHC

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000

Background :The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell prolif- eration, apoptosis and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto- oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.

Product :Ascitic fluid containing 0.03% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :145kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PBT; SCFR; C-Kit; CD117

Immunogen :Purified recombinant fragment of human KIT expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using KIT mouse mAb against Jurkat (1) and Hela (2) cell lysate.

Immunohistochemical analysis of paraffin-embedded human gastrointestinal stromal tumor using KIT mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）