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PRK2 monoclonal antibody

货号: MB21509

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21509

Product Name :PRK2 monoclonal antibody

Swiss-Prot :Q16513

Host :Mouse

Reactivity :Human,Mouse,Rat,Monkey

Applications :WB,IHC,FCM

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000 FC:1/200 - 1/400

Background :Protein-kinase-C-related kinases (PRKs) are part of the lipid-regulated protein kinases (PKC) which also include liver PAK & PKN. Human PRK1 and PRK2 share structurally similar catalytic domains, but less similar N-terminal regulatory regions suggesting different regulatory domain functions. PRK1 and PRK2, as well as a third member of this family, PRK3, show distinct patterns of expression in adult tissues. Additionally, the serine-threonine kinase PRK2 can be specifically cleaved by caspase-3 (and/or caspase-3-like subfamily members) during apoptosis.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :140kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PKN2; PAK2; PRK2; Pak-2; PRKCL2; PRO2042; MGC71074; MGC150606

Immunogen :Purified recombinant fragment of human PRK2 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using PRK2 mouse mAb against PC-12 (1), Cos7 (2), K562 (3), Jurkat (4), Hela (5), A431 (6), C6 (7), NIH/3T3 (8) and HEK293 (9) cell lysate.

Immunohistochemical analysis of paraffin-embedded human prostate tissues using PRK2 mouse mAb with DAB staining.