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ABCG2 monoclonal antibody

货号: MB21478

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB21478

Product Name :ABCG2 monoclonal antibody

Swiss-Prot :Q9UNQ0

Host :Mouse

Reactivity :Human,Mouse,Monkey

Applications :WB,IF

Application_all :WB:1/500 - 1/2000 IF:1/200 - 1/1000

Background :The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.Tissue specificity: Highly expressed in placenta. Low expression in small intestine, liver and colon.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :72kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MRX; MXR; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; CD338; CDw338; EST157481; MGC102821

Immunogen :Purified recombinant fragment of human ABCG2 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using ABCG2 mouse mAb against HepG2 (1), Cos7 (2), Jurkat (3) and NIH/3T3 (4) cell lysate.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）