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CTTN monoclonal antibody

货号: MB21452

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21452

Product Name :CTTN monoclonal antibody

Swiss-Prot :Q14247

Host :Mouse

Reactivity :Human,Mouse

Applications :WB,IHC

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000

Background :This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. (provided by RefSeq)

Product :Ascitic fluid containing 0.03% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :80kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :EMS1; FLJ34459; CTTN

Immunogen :Purified recombinant fragment of human CTTN expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using CTTN mouse mAb against Hela (1), A431 (2), MCF-7 (3), SR-BR-3 (4), HepG2 (5) and NIH/3T3 (6) cell lysate.

Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues (left) and tonsil tissues (right) using CTTN mouse mAb with DAB staining.