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MAP2K6 monoclonal antibody

货号: MB21432

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21432

Product Name :MAP2K6 monoclonal antibody

Swiss-Prot :P52564

Host :Mouse

Reactivity :Human,Mouse

Applications :WB,IHC

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000

Background :This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. Tissue specificity: Isoform 2 is only expressed in skeletal muscle. Isoform 1, on the other hand, is found in skeletal muscle, heart, and in lesser extent in liver or pancreas.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :38kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MEK6; MKK6; MAPKK6; PRKMK6; SAPKK3; MAP2K6

Immunogen :Purified recombinant fragment of human MAP2K6 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using MAP2K6 mouse mAb against HepG2 (1), MCF-7 (2) and NIH/3T3 (3) cell lysate.

Immunohistochemical analysis of paraffin-embedded human ovarian cancer (left) and kidney cancer (right) using MAP2K6 mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）