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ATF2 monoclonal antibody

货号: MB21430

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21430

Product Name :ATF2 monoclonal antibody

Swiss-Prot :P15336

Host :Mouse

Reactivity :Human,Mouse

Applications :WB,IHC

Application_all :WB:1/500 - 1/2000 IHC:1/200 - 1/1000

Background :This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.Tissue specificity: Abundant expression seen in the brain.

Product :Ascitic fluid containing 0.03% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :55kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HB16; CREB2; TREB7; CRE-BP1; MGC111558; ATF2

Immunogen :Purified recombinant fragment of human ATF2 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using ATF2 mouse mAb against NIH/3T3 cell lysate.

Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and brain tissues (right) using ATF2 mouse mAb with DAB staining.

免疫沉淀（IP）

免疫组织化学（IHC）