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SOX2 monoclonal antibody

货号: MB21412

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21412

Product Name :SOX2 monoclonal antibody

Swiss-Prot :P48431

Host :Mouse

Reactivity :Human,Mouse,Rat,Rabbit,Monkey

Applications :WB,IHC,IF,FCM

Application_all :WB:1/500-1/1000 IHC:1/200 - 1/1000 IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

Product :Ascitic fluid containing 0.03% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :34kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ANOP3; MCOPS3

Immunogen :Purified recombinant fragment of human SOX2 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using SOX2 mouse mAb against C6(1),F9(2) cell lysate.

Immunohistochemical analysis of paraffin-embedded human lung cancer tissues (left) and esophageal cancer tissues (right) using SOX2 mouse mAb with DAB staining.

Immunofluorescence analysis of NTERA-2 cells using SOX2 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Flow cytometric analysis of COS7 cells using SOX2 mouse mAb (green) and negative control (red).