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CD86 monoclonal antibody

货号: MB21377

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :MB21377

Product Name :CD86 monoclonal antibody

Swiss-Prot :P42081

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB:1/500 - 1/2000

Background :This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.Tissue specificity: Expressed by activated B-lymphocytes and monocytes.

Product :Ascitic fluid containing 0.03% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :52kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :B70; B7-2; LAB72; CD28LG2; MGC34413; CD86

Immunogen :Purified recombinant fragment of human CD86 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using CD86 mouse mAb against L1210 (1) and MOLT-4 (2) cell lysate.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）