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WDR5 monoclonal antibody

货号: MB21348

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21348

Product Name :WDR5 monoclonal antibody

Swiss-Prot :P61964

Host :Mouse

Reactivity :Human

Applications :WB

Application_all :WB:1/500 - 1/2000

Background :WD-repeat protein 5 (WDR5, also designated BMP-2-induced gene 3 kb or BIG-3) belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in Histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation.

Product :Ascitic fluid containing 0.03% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2b

BiowMW :36.6kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SWD3; BIG-3; WDR5

Immunogen :Purified recombinant fragment of human WDR5 expressed in E. Coli.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using WDR5 mouse mAb against Hela (1) cell lysate.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）