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KDR monoclonal antibody

货号: MB21260

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21260

Product Name :KDR monoclonal antibody

Swiss-Prot :P35968

Host :Mouse

Reactivity :Human

Applications :WB,IF,FCM

Application_all :IF:1/200 - 1/1000 FC:1/200 - 1/400

Background :KDR has also been designated as VEFR-2 (Vascular endothelial growth factor receptor 2), CD309 (cluster of differentiation 309) and Flk1 (fetal liver kinase 1). Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. KDR is one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

Product :Purified antibody in PBS with 0.05% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :152kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :FLK1; CD309; VEGFR; VEGFR2

Immunogen :Purified recombinant extracellular fragment of human KDR (aa20-764) fused with hIgGFc tag expressed in HEK293 cells.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using KDR mouse mAb against extracellular domain of human KDR (aa20-764).

Confocal Immunofluorescence analysis of Hela (left) and HepG2 (right) cells using KDR mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.

免疫沉淀（IP）

免疫组织化学（IHC）