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FLT1 monoclonal antibody

货号: MB21256

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :MB21256

Product Name :FLT1 monoclonal antibody

Swiss-Prot :P17948

Host :Mouse

Reactivity :Human

Applications :WB

Background :Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), also known as FLT1 or VEGFR-1. It is a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

Product :Ascitic fluid containing 0.03% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG1

BiowMW :100kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :FLT; VEGFR1

Immunogen :Purified recombinant extracellular fragment of human FLT1 fused with hIgGFc tag expressed in HEK293 cells.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using FLT1 mouse mAb against extracellular domain of human FLT1.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）