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FGFR1 monoclonal antibody

货号: MB21239

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :MB21239

Product Name :FGFR1 monoclonal antibody

Swiss-Prot :P11362

Host :Mouse

Reactivity :Human

Applications :WB

Background :Fibroblast growth factor receptor 1 (FGFR1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. FGFR1 has been shown to be associated with Pfeiffer syndrome. It is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction.

Product :Ascitic fluid containing 0.03% sodium azide.

Purification&Purity :The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Mouse IgG2b

BiowMW :92kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CEK; FLG; OGD; FLT2; KAL2; BFGFR; CD331; FGFBR; HBGFR

Immunogen :Purified recombinant extracellular fragment of human FGFR1 (aa22-376) fused with hIgGFc tag expressed in HEK293 cells.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis using FGFR1 mouse mAb against extracellular domain of human FGFR1 (aa22-376).

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）